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Omicron XBB.1.5 is most transmissible subvariant, WHO says

INBV News by INBV News
January 5, 2023
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Omicron XBB.1.5 is most transmissible subvariant, WHO says
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XBB.1.5 strain, January 4, 2023, Suqian, Jiangsu, China.

CFOTO | Future Publishing | Getty Images

The XBB.1.5 omicron subvariant that is currently dominating the U.S. is essentially the most contagious version of Covid-19 yet, but it surely doesn’t appear to make people sicker, in accordance with the World Health Organization.

Maria Van Kerkhove, the WHO’s Covid-19 technical lead, said global health officials are anxious about how quickly the subvariant is spreading within the northeastern U.S. The number of individuals infected with XBB.1.5 has been doubling within the U.S. about every two weeks, making it essentially the most common variant circulating within the country.

“It’s essentially the most transmissible subvariant that has been detected yet,” Van Kerkhove told reporters during a press conference in Geneva on Wednesday. “The explanation for this are the mutations which can be inside this subvariant of omicron allowing this virus to stick to the cell and replicate easily.”

It has been detected in 29 countries thus far but it surely may very well be much more widespread, Van Kerkhove said. Tracking Covid variants has develop into difficult as genomic sequencing declines the world over, she said.

The WHO doesn’t have any data yet on the severity of XBB.1.5, but there is no indication in the mean time that it makes people sicker than previous versions of omicron, Van Kerkhove said. The WHO’s advisory group that tracks Covid variants is conducting a risk assessment on XBB.1.5 that it is going to publish in the approaching days, she said.

“The more this virus circulates the more opportunities it is going to must change,” Van Kerkhove said. “We do expect further waves of infection world wide but that does not must translate into further waves of death because our countermeasures proceed to work.”

Scientists say XBB.1.5 is about pretty much as good at dodging antibodies from vaccines and infection as its XBB and XBB.1 relatives, which were two of essentially the most immune evasive subvariants yet. But XBB.1.5 has a mutation that makes it bind more tightly to cells, which supplies it a growth advantage.

As XBB.1.5 rapidly spreads within the U.S., China is battling a surge of cases and hospitalizations after abandoning its zero-Covid policy in response to social unrest late last 12 months. U.S. and global health officials have said Beijing just isn’t sharing enough data on the surge with the international community.

“We proceed to ask China for more rapid regular reliable data on hospitalizations and deaths as well more comprehensive real-time viral sequencing,” WHO Director-General Tedros Adhanom Ghebreyesus told reporters in Geneva on Wednesday.

A growing number of nations, including the U.S., are requiring airline passengers from China to check negative for Covid before boarding their flights. China’s foreign ministry has said such measures lack a scientific basis and has accused the governments of manipulating Covid for political purposes. However the WHO director-general said the necessities are comprehensible given the limited data coming out of China.

“With circulation in China so high and comprehensive data not forthcoming, it’s comprehensible that some countries are taking steps they imagine will protect their very own residents,” Tedros said Wednesday.

Beijing’s Center for Disease Control and Prevention shared data Tuesday with the WHO indicating BA.5 sublineages, BA.5.2 and BF.7, account for about 98% of all infections within the country. But Van Kerkhove said China just isn’t sharing enough sequencing data from across the vast country.

“It is not only a matter of knowing what variants are circulating,” Van Kerkhove said. “We want the worldwide community to evaluate these, to have a look at mutation by mutation to find out if any of those are recent variants circulating in China but in addition world wide.”

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