Bills vs. Texans prediction: Week 12 ‘Thursday Night Football’ picks, odds

The Bills head to Houston to tackle the Texans in a key Thursday night AFC matchup. 

While Buffalo improved to 7-3 with a win over the Buccaneers last Sunday, their biggest weakness showed its face once more. 

Tampa Bay ran wild against the Bills, rushing for a season-high 202 yards. 

Third-string running back Sean Tucker had a profession day, going for 106 yards on the bottom with three total touchdowns. 

Tucker had six rushes of 10-plus yards, including a 43-yard rating within the second quarter. 

It was a continuation of the Bills’ entire season, and this week their run defense will face one of the crucial explosive young running backs within the NFL right as he’s hitting his stride. 

Heading into Week 12, the Bills have allowed the 2nd-most rushing yards per attempt (5.4) and 2nd-most rushing yards per game (153) this season. 

That’s excellent news for Woody Marks. 

The USC product has taken over the Texans’ backfield from veteran Nick Chubb, getting double-digit rushing attempts in each of his last five games, including a season-high 18 last week. 

Over the past 4 weeks, in a stretch that included some tough run defense just like the Broncos, Jaguars, and 49ers, Marks has gone over 60 yards on the bottom in two games. 

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After weeks of sharing the backfield, Marks has essentially been a real RB1 for Houston during the last two weeks, playing in 80 percent of their snaps and 66 percent last week, which were his two highest totals this season. 

Search for Marks to have himself one other solid showing on Thursday night. 

The play: Woody Marks Over 57.5 rushing yards (-120, bet365 Sportsbook)

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Dylan Svoboda is a flexible author and analyst across many sports. He’s particularly knowledgeable in regards to the big three — MLB, the NFL and the NBA.